Chair: Nicole Fischer (Hamburg-Eppendorf, Germany)

09:00-09:05 Nicole Fischer, Jürgen Becker, John Paoli & Weng-Onn Lui
Welcome address

09:05-09:35 James A DeCaprio (Boston, USA)
Identifying therapeutic targets in MCPyV-positive Merkel cell carcinoma

09:35-10:05 Iwona Lugowska (Warsaw, Poland)
Merkel cell carcinoma: ESMO–EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up

10:05-10:20 Emily Gong (Seattle, USA)
Immunosuppressed Merkel cell carcinoma patients frequently respond to immunotherapy but with significantly shorter durability: a 183-patient cohort

10:20-10:35  Silvia Albertini (Hamburg, Germany)
Merkel Cell Polyomavirus efficiently infects iPS-derived skin organoids

10:35-11:00 Flash poster presentations (2 minutes/presentation)     
Büke Celikdemir (Würzburg, Germany), Sara Passerini (Rome, Italy), Wen Xu (Brisbane, Australia) (2 posters), Hao Shi (Stockholm, Sweden), Meng Luo (Essen, Germany), Hannah Björn Andtback (Stockholm, Sweden), Libuse Janska (Stockholm, Sweden), Yajie Yang (Stockholm, Sweden) and Julian Kött (Hamburg, Germany)

11:00-11:30 Coffee break   

11:30-12:15 Poster session                

12.15-12:30 Haroldo Rodriguez (Seattle, USA) 
Germinal center B cell response in MCPyV-driven Merkel cell carcinoma associates with disease outcomes

12:30-13:00 Martin Enge (Stockholm, Sweden)
Gene dosage heterogeneity in cancer

13:00-14:00 Lunch 

Chair: Jürgen Becker (Essen, Germany)

14:00-14:30 Thibault Kervarrec (Tours, France)
Adcitmer®, a new CD56-targeting monomethyl auristatin E-conjugated antibody, is a potential therapeutic approach in Merkel cell carcinoma

14:30-15:00 Mads Hald Andersen (Copenhagen, Denmark)
Immune modulatory vaccines for cancer therapy

15:00-15:15 Isaac Brownell (Bethesda, USA)
CDK inhibitors disrupt mRNA processing and synergize with Bcl-xL inhibitors in Merkel cell carcinoma

15:15-15:30 Krista Lachance (Seattle, USA)
Working together to find a cure: The Merkel cell carcinoma collaborative (MC3)

15:30-16:00  Coffee break   

16:00-16:30 Gustav Ullenhag (Uppsala, Sweden)
The role of imaging during follow-up after radical surgery of stage IIB-C and III cutaneous melanoma and Merkel cell carcinoma: Survival results from an interim analysis of a randomized prospective multicenter study (TRIM)

16:30-17:00 Klaus Pantel (Hamburg-Eppendorf, Germany)
Liquid biopsy: From discovery to clinical implementation

17:00-17:15 Georg Lodde (Essen, Germany)
Only early adjuvant radiotherapy, particularly of the tumor bed rather than the lymph node region, improves prognosis in Merkel cell carcinoma: Results from the prospective German MCC registry

17:15-17:30 Kuan Cheok Lei (Essen, Germany)
High-definition spatial transcriptomics dissects MCC heterogeneity underlying epidermotropism